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Can I run gmer.exe in Win 7 Safe mode?

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Hi I am new to this thread.
I suspect my HP Win 7 laptop is infected with malware. I read 1st step instructions before posting. My laptop is now forced to start in safe mode without any reasons. Can I run dds and gmer.exe scans in safe mode? My McAfee Total Protection already showed relatime scan is disabled (I did not invoke it). This posting is made by my other computer. To save time, I already started the gmer.exe scan on my laptop suspected of malware infection. It is taking more than 2 hours now. Let me know if I need to do things differently. Plz help.

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